Use of a resin-bound synthetic peptide for identifying a neutralizing antigenic determinant associated with the human immunodeficiency virus envelope.
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چکیده
منابع مشابه
Antigenic Properties of the Human Immunodeficiency Virus Envelope Glycoprotein Gp120 on Virions Bound to Target Cells
The HIV-1 envelope glycoprotein, gp120, undergoes multiple molecular interactions and structural rearrangements during the course of host cell attachment and viral entry, which are being increasingly defined at the atomic level using isolated proteins. In comparison, antigenic markers of these dynamic changes are essentially unknown for single HIV-1 particles bound to target cells. Such markers...
متن کاملConversion of an Intmunogenic Human Immunodeficiency Virus ( HIV ) Envelope Synthetic Peptide to a
From the Departments of "Medicine, *Surgery, and SMicrobiology and Imm.nology, the Duke Center For AIDS Research, Duke University Medscal Center, Durham, North Carohna 27710, the IINew Mexico State Umverstty Primate Center, Alamogordo, New Mexico 88310; and the 82 Program, Program Resources, Inc./DlmCo~, National Cancer Instttute, Frederick Cancer Research and Development Center, Frederick, Mar...
متن کاملCorrection: Antigenic Properties of the Human Immunodeficiency Virus Envelope Glycoprotein Gp120 on Virions Bound to Target Cells
to correct Figures 5 and 6, which were both re-sized during the typesetting process. The publisher apologizes for the errors. Please download this article again to view the correct version. is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author a...
متن کاملdeterminant of the hankel matrix with binomial entries
abstract in this thesis at first we comput the determinant of hankel matrix with enteries a_k (x)=?_(m=0)^k??((2k+2-m)¦(k-m)) x^m ? by using a new operator, ? and by writing and solving differential equation of order two at points x=2 and x=-2 . also we show that this determinant under k-binomial transformation is invariant.
15 صفحه اولA Rationally Designed Synthetic Peptide Mimic of a Discontinuous Viral Antigenic Site Elicits Neutralizing Antibodies
Synthetic peptides have a successful record of immunological applications as models of continuous epitopes or immunogens capable of eliciting antibodies of predetermined specificity.1 The peptide approach has been crucial for the molecular dissection of protein antigens and has also resulted in useful applications, including peptide-based vaccines.2 The success of the methodology, however, tend...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1987
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)45641-4